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KMID : 0363619940150020156
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Journal of Korean Oriental Medicine
1994 Volume.15 No. 2 p.156 ~ p.172
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An experimental research of the effect of Gamichunggantang
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Hong Sang-Hoon
Lee Jang-Hoon
Woo Hong-Jung
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Abstract
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This study was performed to evaluate the effect of the Gamichunggantang on recovering from liver injury induced by d-galactosamine and {alpha}-naphthylisothiocyanate. and following results were obtained. 1. The increases of the serum GOT. GPT activities in mice induced by d-galactosamine and {alpha}-naphthylisothiocyanate were inhibited significantly by the administration of the Gamichunggantang. 2. The increases of the total cholesterol. triglyceride and blood urea nitrogen levels in mice induced by d-galactosamine and {alpha}-naphthylisothiocyanate were significantly inhibited by the administration of the Gamichunggantang. 3. The increase of the ALP activity in mice following liver injury induced by d-galactosamine and {alpha}-naphthylisothiocyanate were inhibited to an extend. but it was not significant. 4. It is considered that the efficacy of the Gamichunggantang on liver cell injury depends on its concentration rate.
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